Anti-ACE2 Antibody
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxypeptidases and has considerable homology to the human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7.
The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2 (COVID-19 virus)
| Cat # +Size | A2072-100 |
|---|---|
| Size | 100 μg |
| Antibody Target | ACE2 |
| Alternate Name | Angiotensin-converting enzyme 2; ACE-related carboxypeptidase; Angiotensin-converting enzyme homolog; ACEH; Metalloprotease MPROT15 |
| Host | Rabbit |
| Antibody Type | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant Human Angiotensin-converting enzyme 2 protein (395-638 aa) |
| Accession # | Q9BYF1 |
| Gene ID | 59272 |
| Appearance | Colorless liquid |
| Formulation | In 0.01 M PBS, pH 7.4, 50% Glycerol, 0.03% proclin 300 |
| Purification | Affinity purified |
| Species Reactivity | Human |
| Application | Immunofluorescence (IF), Immunohistochemistry (IHC) |
| Application & Usage | IHC 1:20-1:200, IF 1:50-1:200 |
| Handling | The antibody solution should be gently mixed before use. |
| Storage Conditions | -20ºC |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |