Coronaviruses are large, enveloped, positive-sense RNA viruses that are known to affect humans, birds, and mammals. These viruses have a genome length of 30 kb. The 5′-terminal of the viral genome encodes a polyprotein that upon cleavage yields several non-structural proteins that play important roles in viral transcription and replication. The 3′-terminal encodes 4 structural proteins, namely, Spike (S), Envelope (E), Membrane (M), and Nucleocapsid (N) that have an essential role in the synthesis of viral RNA and viral replication.
There are 6 known Coronaviruses that infect humans. Of these, two are known to cause severe diseases with high rates of mortality: Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle-East Respiratory Syndrome Coronavirus (MERS-CoV). Recently, a group of Chinese scientists discovered another strain of Coronavirus that caused a massive viral outbreak in China.
This virus is more deadly than SARS-CoV and MERS-CoV combined and is named SARS-CoV-2 (previously COVID-19). Since very little information available regarding the role of the COVID-19 proteins in viral pathogenesis and replication, not many treatment options are available. In addition to this, there are limited antibodies available in the market to detect these proteins.
BioVision is pleased to announce the launch of Coronavirus Antibodies, the first in the market. These antibodies specialize in detecting the Coronavirus disease 2019 nucleoprotein (SARS-CoV-2, COVID-19), SARS, and MERS. They have been tested using research techniques such as Western Blot, ELISA, Immunofluorescence, and Immunohistochemistry. These antibodies are available in both polyclonal and monoclonal formats and can readily be shipped worldwide.
Can these antibodies detect COVID-19/SARS-CoV-2?
Yes, some of our Coronavirus antibodies can detect COVID-19/SARS-CoV-2.